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Kavain, the Major Constituent of the Anxiolytic Kava Extract, Potentiates GABAA Receptors: Functiona...

Kavain, the Major Constituent of the Anxiolytic Kava Extract, Potentiates GABAA Receptors: Functiona...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1799178823

Kavain, the Major Constituent of the Anxiolytic Kava Extract, Potentiates GABAA Receptors: Functional Characteristics and Molecular Mechanism

About this item

Full title

Kavain, the Major Constituent of the Anxiolytic Kava Extract, Potentiates GABAA Receptors: Functional Characteristics and Molecular Mechanism

Publisher

United States: Public Library of Science

Journal title

PloS one, 2016-06, Vol.11 (6), p.e0157700-e0157700

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Extracts of the pepper plant kava (Piper methysticum) are effective in alleviating anxiety in clinical trials. Despite the long-standing therapeutic interest in kava, the molecular target(s) of the pharmacologically active constituents, kavalactones have not been established. γ-Aminobutyric acid type A receptors (GABAARs) are assumed to be the in v...

Alternative Titles

Full title

Kavain, the Major Constituent of the Anxiolytic Kava Extract, Potentiates GABAA Receptors: Functional Characteristics and Molecular Mechanism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1799178823

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1799178823

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0157700

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