Kavain, the Major Constituent of the Anxiolytic Kava Extract, Potentiates GABAA Receptors: Functiona...
Kavain, the Major Constituent of the Anxiolytic Kava Extract, Potentiates GABAA Receptors: Functional Characteristics and Molecular Mechanism
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Extracts of the pepper plant kava (Piper methysticum) are effective in alleviating anxiety in clinical trials. Despite the long-standing therapeutic interest in kava, the molecular target(s) of the pharmacologically active constituents, kavalactones have not been established. γ-Aminobutyric acid type A receptors (GABAARs) are assumed to be the in v...
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Kavain, the Major Constituent of the Anxiolytic Kava Extract, Potentiates GABAA Receptors: Functional Characteristics and Molecular Mechanism
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TN_cdi_plos_journals_1799178823
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1799178823
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0157700