Co-Culture of Tumor Spheroids and Fibroblasts in a Collagen Matrix-Incorporated Microfluidic Chip Mi...
Co-Culture of Tumor Spheroids and Fibroblasts in a Collagen Matrix-Incorporated Microfluidic Chip Mimics Reciprocal Activation in Solid Tumor Microenvironment
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Multicellular 3D culture and interaction with stromal components are considered essential elements in establishing a 'more clinically relevant' tumor model. Matrix-embedded 3D cultures using a microfluidic chip platform can recapitulate the microscale interaction within tumor microenvironments. As a major component of tumor microenvironment, cancer...
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Full title
Co-Culture of Tumor Spheroids and Fibroblasts in a Collagen Matrix-Incorporated Microfluidic Chip Mimics Reciprocal Activation in Solid Tumor Microenvironment
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TN_cdi_plos_journals_1802586006
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1802586006
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0159013
