Fractionated Radiotherapy with 3 x 8 Gy Induces Systemic Anti-Tumour Responses and Abscopal Tumour I...
Fractionated Radiotherapy with 3 x 8 Gy Induces Systemic Anti-Tumour Responses and Abscopal Tumour Inhibition without Modulating the Humoral Anti-Tumour Response
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Habets, Thomas H P M , Oth, Tammy , Houben, Ans W , Huijskens, Mirelle J A J , Senden-Gijsbers, Birgit L M G , Schnijderberg, Melanie C A , Brans, Boudewijn , Dubois, Ludwig J , Lambin, Philippe , De Saint-Hubert, Marijke , Germeraad, Wilfred T V , Tilanus, Marcel G J , Mottaghy, Felix M , Bos, Gerard M J and Vanderlocht, Joris
Publisher
United States: Public Library of Science
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English
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United States: Public Library of Science
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Contents
Accumulating evidence indicates that fractionated radiotherapy (RT) can result in distant non-irradiated (abscopal) tumour regression. Although preclinical studies indicate the importance of T cells in this infrequent phenomenon, these studies do not preclude that other immune mechanisms exhibit an addition role in the abscopal effect. We therefore...
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Full title
Fractionated Radiotherapy with 3 x 8 Gy Induces Systemic Anti-Tumour Responses and Abscopal Tumour Inhibition without Modulating the Humoral Anti-Tumour Response
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TN_cdi_plos_journals_1805472185
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1805472185
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0159515
