Platelet Apoptosis in Adult Immune Thrombocytopenia: Insights into the Mechanism of Damage Triggered...
Platelet Apoptosis in Adult Immune Thrombocytopenia: Insights into the Mechanism of Damage Triggered by Auto-Antibodies
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Mechanisms leading to decreased platelet count in immune thrombocytopenia (ITP) are heterogeneous. This study describes increased platelet apoptosis involving loss of mitochondrial membrane potential (ΔΨm), caspase 3 activation (aCasp3) and phosphatidylserine (PS) externalization in a cohort of adult ITP patients. Apoptosis was not related to plate...
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Platelet Apoptosis in Adult Immune Thrombocytopenia: Insights into the Mechanism of Damage Triggered by Auto-Antibodies
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TN_cdi_plos_journals_1812517470
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1812517470
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0160563