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Natural Cubic Spline Regression Modeling Followed by Dynamic Network Reconstruction for the Identifi...

Natural Cubic Spline Regression Modeling Followed by Dynamic Network Reconstruction for the Identifi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1812536282

Natural Cubic Spline Regression Modeling Followed by Dynamic Network Reconstruction for the Identification of Radiation-Sensitivity Gene Association Networks from Time-Course Transcriptome Data

About this item

Full title

Natural Cubic Spline Regression Modeling Followed by Dynamic Network Reconstruction for the Identification of Radiation-Sensitivity Gene Association Networks from Time-Course Transcriptome Data

Publisher

United States: Public Library of Science

Journal title

PloS one, 2016-08, Vol.11 (8), p.e0160791-e0160791

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Gene expression time-course experiments allow to study the dynamics of transcriptomic changes in cells exposed to different stimuli. However, most approaches for the reconstruction of gene association networks (GANs) do not propose prior-selection approaches tailored to time-course transcriptome data. Here, we present a workflow for the identificat...

Alternative Titles

Full title

Natural Cubic Spline Regression Modeling Followed by Dynamic Network Reconstruction for the Identification of Radiation-Sensitivity Gene Association Networks from Time-Course Transcriptome Data

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1812536282

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1812536282

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0160791

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