Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardio...
Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Mediator, an evolutionarily conserved multi-protein complex consisting of about 30 subunits, is a key component of the polymerase II mediated gene transcription. Germline deletion of the Mediator subunit 1 (Med1) of the Mediator in mice results in mid-gestational embryonic lethality with developmental impairment of multiple organs including heart....
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Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice
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TN_cdi_plos_journals_1813193922
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1813193922
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0160755
