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Feasibility Study of the Permeability and Uptake of Mesoporous Silica Nanoparticles across the Blood...

Feasibility Study of the Permeability and Uptake of Mesoporous Silica Nanoparticles across the Blood...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1813194438

Feasibility Study of the Permeability and Uptake of Mesoporous Silica Nanoparticles across the Blood-Brain Barrier

About this item

Full title

Feasibility Study of the Permeability and Uptake of Mesoporous Silica Nanoparticles across the Blood-Brain Barrier

Publisher

United States: Public Library of Science

Journal title

PloS one, 2016-08, Vol.11 (8), p.e0160705

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Drug delivery into the brain is impeded by the blood-brain-barrier (BBB) that filters out the vast majority of drugs after systemic administration. In this work, we assessed the transport, uptake and cytotoxicity of promising drug nanocarriers, mesoporous silica nanoparticles (MSNs), in in vitro models of the BBB. RBE4 rat brain endothelial cells a...

Alternative Titles

Full title

Feasibility Study of the Permeability and Uptake of Mesoporous Silica Nanoparticles across the Blood-Brain Barrier

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1813194438

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1813194438

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0160705

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