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Widespread Shortening of 3' Untranslated Regions and Increased Exon Inclusion Are Evolutionarily Con...

Widespread Shortening of 3' Untranslated Regions and Increased Exon Inclusion Are Evolutionarily Con...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1829443491

Widespread Shortening of 3' Untranslated Regions and Increased Exon Inclusion Are Evolutionarily Conserved Features of Innate Immune Responses to Infection

About this item

Full title

Widespread Shortening of 3' Untranslated Regions and Increased Exon Inclusion Are Evolutionarily Conserved Features of Innate Immune Responses to Infection

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2016-09, Vol.12 (9), p.e1006338-e1006338

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The contribution of pre-mRNA processing mechanisms to the regulation of immune responses remains poorly studied despite emerging examples of their role as regulators of immune defenses. We sought to investigate the role of mRNA processing in the cellular responses of human macrophages to live bacterial infections. Here, we used mRNA sequencing to q...

Alternative Titles

Full title

Widespread Shortening of 3' Untranslated Regions and Increased Exon Inclusion Are Evolutionarily Conserved Features of Innate Immune Responses to Infection

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1829443491

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1829443491

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1006338

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