Sequence-Specific Targeting of Bacterial Resistance Genes Increases Antibiotic Efficacy
Sequence-Specific Targeting of Bacterial Resistance Genes Increases Antibiotic Efficacy
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The lack of effective and well-tolerated therapies against antibiotic-resistant bacteria is a global public health problem leading to prolonged treatment and increased mortality. To improve the efficacy of existing antibiotic compounds, we introduce a new method for strategically inducing antibiotic hypersensitivity in pathogenic bacteria. Followin...
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Full title
Sequence-Specific Targeting of Bacterial Resistance Genes Increases Antibiotic Efficacy
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TN_cdi_plos_journals_1829444084
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1829444084
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ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.1002552