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Sequence-Specific Targeting of Bacterial Resistance Genes Increases Antibiotic Efficacy

Sequence-Specific Targeting of Bacterial Resistance Genes Increases Antibiotic Efficacy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1829444084

Sequence-Specific Targeting of Bacterial Resistance Genes Increases Antibiotic Efficacy

About this item

Full title

Sequence-Specific Targeting of Bacterial Resistance Genes Increases Antibiotic Efficacy

Publisher

United States: Public Library of Science

Journal title

PLoS biology, 2016-09, Vol.14 (9), p.e1002552

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The lack of effective and well-tolerated therapies against antibiotic-resistant bacteria is a global public health problem leading to prolonged treatment and increased mortality. To improve the efficacy of existing antibiotic compounds, we introduce a new method for strategically inducing antibiotic hypersensitivity in pathogenic bacteria. Followin...

Alternative Titles

Full title

Sequence-Specific Targeting of Bacterial Resistance Genes Increases Antibiotic Efficacy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1829444084

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1829444084

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.1002552

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