Screening and Development of New Inhibitors of FtsZ from M. Tuberculosis
Screening and Development of New Inhibitors of FtsZ from M. Tuberculosis
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
A variety of commercial analogs and a newer series of Sulindac derivatives were screened for inhibition of M. tuberculosis (Mtb) in vitro and specifically as inhibitors of the essential mycobacterial tubulin homolog, FtsZ. Due to the ease of preparing diverse analogs and a favorable in vivo pharmacokinetic and toxicity profile of a representative a...
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Full title
Screening and Development of New Inhibitors of FtsZ from M. Tuberculosis
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TN_cdi_plos_journals_1830874197
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1830874197
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0164100
