Exploring Flexibility of Progesterone Receptor Ligand Binding Domain Using Molecular Dynamics
Exploring Flexibility of Progesterone Receptor Ligand Binding Domain Using Molecular Dynamics
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Progesterone receptor (PR), a member of nuclear receptor (NR) superfamily, plays a vital role for female reproductive tissue development, differentiation and maintenance. PR ligand, such as progesterone, induces conformation changes in PR ligand binding domain (LBD), thus mediates subsequent gene regulation cascades. PR LBD may adopt different conf...
Alternative Titles
Full title
Exploring Flexibility of Progesterone Receptor Ligand Binding Domain Using Molecular Dynamics
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1837222082
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1837222082
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0165824
