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Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and D...

Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and D...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1840921535

Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose–Efficacy Modeling

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Artemisinin resistance observed in Southeast Asia threatens the continued use of artemisinin-based combination therapy in endemic countries. Additionally, the diversity of chemical mode of action in the global portfolio of marketed antimalarials is extremely limited. Addressing the urgent need for the development of new antimalarials, a chemical cl...

Alternative Titles

Full title

Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose–Efficacy Modeling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1840921535

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1840921535

Other Identifiers

ISSN

1549-1676,1549-1277

E-ISSN

1549-1676

DOI

10.1371/journal.pmed.1002138

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