Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and D...
Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose–Efficacy Modeling
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Author / Creator
Le Bihan, Amélie , de Kanter, Ruben , Angulo-Barturen, Iñigo , Binkert, Christoph , Boss, Christoph , Brun, Reto , Brunner, Ralf , Buchmann, Stephan , Burrows, Jeremy , Dechering, Koen J. , Delves, Michael , Ewerling, Sonja , Ferrer, Santiago , Fischli, Christoph , Gamo–Benito, Francisco Javier , Gnädig, Nina F. , Heidmann, Bibia , Jiménez-Díaz, María Belén , Leroy, Didier , Martínez, Maria Santos , Meyer, Solange , Moehrle, Joerg J. , Ng, Caroline L. , Noviyanti, Rintis , Ruecker, Andrea , Sanz, Laura María , Sauerwein, Robert W. , Scheurer, Christian , Schleiferboeck, Sarah , Sinden, Robert , Snyder, Christopher , Straimer, Judith , Wirjanata, Grennady , Marfurt, Jutta , Price, Ric N. , Weller, Thomas , Fischli, Walter , Fidock, David A. , Clozel, Martine and Wittlin, Sergio
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
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More information
Scope and Contents
Contents
Artemisinin resistance observed in Southeast Asia threatens the continued use of artemisinin-based combination therapy in endemic countries. Additionally, the diversity of chemical mode of action in the global portfolio of marketed antimalarials is extremely limited. Addressing the urgent need for the development of new antimalarials, a chemical cl...
Alternative Titles
Full title
Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose–Efficacy Modeling
Authors, Artists and Contributors
Author / Creator
de Kanter, Ruben
Angulo-Barturen, Iñigo
Binkert, Christoph
Boss, Christoph
Brun, Reto
Brunner, Ralf
Buchmann, Stephan
Burrows, Jeremy
Dechering, Koen J.
Delves, Michael
Ewerling, Sonja
Ferrer, Santiago
Fischli, Christoph
Gamo–Benito, Francisco Javier
Gnädig, Nina F.
Heidmann, Bibia
Jiménez-Díaz, María Belén
Leroy, Didier
Martínez, Maria Santos
Meyer, Solange
Moehrle, Joerg J.
Ng, Caroline L.
Noviyanti, Rintis
Ruecker, Andrea
Sanz, Laura María
Sauerwein, Robert W.
Scheurer, Christian
Schleiferboeck, Sarah
Sinden, Robert
Snyder, Christopher
Straimer, Judith
Wirjanata, Grennady
Marfurt, Jutta
Price, Ric N.
Weller, Thomas
Fischli, Walter
Fidock, David A.
Clozel, Martine
Wittlin, Sergio
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1840921535
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1840921535
Other Identifiers
ISSN
1549-1676,1549-1277
E-ISSN
1549-1676
DOI
10.1371/journal.pmed.1002138