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Mammalian-Specific Central Myelin Protein Opalin Is Redundant for Normal Myelination: Structural and...

Mammalian-Specific Central Myelin Protein Opalin Is Redundant for Normal Myelination: Structural and...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1841158211

Mammalian-Specific Central Myelin Protein Opalin Is Redundant for Normal Myelination: Structural and Behavioral Assessments

About this item

Full title

Mammalian-Specific Central Myelin Protein Opalin Is Redundant for Normal Myelination: Structural and Behavioral Assessments

Publisher

United States: Public Library of Science

Journal title

PloS one, 2016-11, Vol.11 (11), p.e0166732-e0166732

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Opalin, a central nervous system-specific myelin protein phylogenetically unique to mammals, has been suggested to play a role in mammalian-specific myelin. To elucidate the role of Opalin in mammalian myelin, we disrupted the Opalin gene in mice and analyzed the impacts on myelination and behavior. Opalin-knockout (Opalin-/-) mice were born at a M...

Alternative Titles

Full title

Mammalian-Specific Central Myelin Protein Opalin Is Redundant for Normal Myelination: Structural and Behavioral Assessments

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1841158211

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1841158211

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0166732

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