TGFbeta Induces Binucleation/Polyploidization in Hepatocytes through a Src-Dependent Cytokinesis Fai...
TGFbeta Induces Binucleation/Polyploidization in Hepatocytes through a Src-Dependent Cytokinesis Failure
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
In all mammals, the adult liver shows binucleated as well as mononucleated polyploid hepatocytes. The hepatic polyploidization starts after birth with an extensive hepatocyte binucleation and generates hepatocytes of several ploidy classes. While the functional significance of hepatocyte polyploidy is becoming clearer, how it is triggered and maint...
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Full title
TGFbeta Induces Binucleation/Polyploidization in Hepatocytes through a Src-Dependent Cytokinesis Failure
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TN_cdi_plos_journals_1844332694
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1844332694
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0167158
