TP53 Polymorphisms and Colorectal Cancer Risk in Patients with Lynch Syndrome in Taiwan: A Retrospec...
TP53 Polymorphisms and Colorectal Cancer Risk in Patients with Lynch Syndrome in Taiwan: A Retrospective Cohort Study
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United States: Public Library of Science
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English
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United States: Public Library of Science
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TP53 encodes p53, which has a crucial role in modulating genes that regulate defense against cancer development. This study investigated whether TP53 polymorphisms are associated with colorectal cancer (CRC) in patients with Lynch syndrome and whether TP53 interacts with lifestyle factors to modify CRC risk.
We identified 260 MLH1 and MSH2 germl...
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TP53 Polymorphisms and Colorectal Cancer Risk in Patients with Lynch Syndrome in Taiwan: A Retrospective Cohort Study
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TN_cdi_plos_journals_1845247370
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1845247370
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0167354