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TP53 Polymorphisms and Colorectal Cancer Risk in Patients with Lynch Syndrome in Taiwan: A Retrospec...

TP53 Polymorphisms and Colorectal Cancer Risk in Patients with Lynch Syndrome in Taiwan: A Retrospec...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1845247370

TP53 Polymorphisms and Colorectal Cancer Risk in Patients with Lynch Syndrome in Taiwan: A Retrospective Cohort Study

About this item

Full title

TP53 Polymorphisms and Colorectal Cancer Risk in Patients with Lynch Syndrome in Taiwan: A Retrospective Cohort Study

Publisher

United States: Public Library of Science

Journal title

PloS one, 2016-12, Vol.11 (12), p.e0167354-e0167354

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

TP53 encodes p53, which has a crucial role in modulating genes that regulate defense against cancer development. This study investigated whether TP53 polymorphisms are associated with colorectal cancer (CRC) in patients with Lynch syndrome and whether TP53 interacts with lifestyle factors to modify CRC risk.
We identified 260 MLH1 and MSH2 germl...

Alternative Titles

Full title

TP53 Polymorphisms and Colorectal Cancer Risk in Patients with Lynch Syndrome in Taiwan: A Retrospective Cohort Study

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1845247370

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1845247370

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0167354

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