TLR3-Induced Maturation of Murine Dendritic Cells Regulates CTL Responses by Modulating PD-L1 Traffi...
TLR3-Induced Maturation of Murine Dendritic Cells Regulates CTL Responses by Modulating PD-L1 Trafficking
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Targeting TLR3 through formulations of polyI:C is widely studied as an adjuvant in cancer immunotherapy. The efficacy of such targeting has been shown to increase in combination with anti-PD-L1 treatment. Nevertheless, the mechanistic details of the effect of polyI:C on DC maturation and the impact on T-DC interactions upon PD-L1 blockade is largel...
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Full title
TLR3-Induced Maturation of Murine Dendritic Cells Regulates CTL Responses by Modulating PD-L1 Trafficking
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TN_cdi_plos_journals_1845404380
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1845404380
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0167057
