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Effects on P-Glycoprotein Expression after Blood-Brain Barrier Disruption Using Focused Ultrasound a...

Effects on P-Glycoprotein Expression after Blood-Brain Barrier Disruption Using Focused Ultrasound a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1855060754

Effects on P-Glycoprotein Expression after Blood-Brain Barrier Disruption Using Focused Ultrasound and Microbubbles

About this item

Full title

Effects on P-Glycoprotein Expression after Blood-Brain Barrier Disruption Using Focused Ultrasound and Microbubbles

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-01, Vol.12 (1), p.e0166061-e0166061

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Many blood-borne substances attempting to pass through the luminal membrane of brain endothelial cells are acted upon by a variety of metabolizing enzymes or are actively expelled back into the capillary lumen by embedded efflux transporters, such as Permeability-glycoprotein (Pgp). Overexpression of this protein has also been linked to multidrug r...

Alternative Titles

Full title

Effects on P-Glycoprotein Expression after Blood-Brain Barrier Disruption Using Focused Ultrasound and Microbubbles

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1855060754

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1855060754

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0166061

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