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Reduced expression of argininosuccinate synthetase 1 has a negative prognostic impact in patients wi...

Reduced expression of argininosuccinate synthetase 1 has a negative prognostic impact in patients wi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1867150912

Reduced expression of argininosuccinate synthetase 1 has a negative prognostic impact in patients with pancreatic ductal adenocarcinoma

About this item

Full title

Reduced expression of argininosuccinate synthetase 1 has a negative prognostic impact in patients with pancreatic ductal adenocarcinoma

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-02, Vol.12 (2), p.e0171985-e0171985

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Argininosuccinate synthetase 1 (ASS1), the rate-limiting enzyme for arginine biosynthesis, is expressed in many types of human malignancies. Recent studies showed that ASS1 may have tumor suppressor function and that ASS1 deficiency is associated with clinical aggressiveness in nasopharyngeal carcinoma, myxofibrosarcomas and bladder cancer. The goa...

Alternative Titles

Full title

Reduced expression of argininosuccinate synthetase 1 has a negative prognostic impact in patients with pancreatic ductal adenocarcinoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1867150912

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1867150912

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0171985

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