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Lung Basal Stem Cells Rapidly Repair DNA Damage Using the Error-Prone Nonhomologous End-Joining Path...

Lung Basal Stem Cells Rapidly Repair DNA Damage Using the Error-Prone Nonhomologous End-Joining Path...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1869001603

Lung Basal Stem Cells Rapidly Repair DNA Damage Using the Error-Prone Nonhomologous End-Joining Pathway

About this item

Full title

Lung Basal Stem Cells Rapidly Repair DNA Damage Using the Error-Prone Nonhomologous End-Joining Pathway

Publisher

United States: Public Library of Science

Journal title

PLoS biology, 2017-01, Vol.15 (1), p.e2000731

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Lung squamous cell carcinoma (SqCC), the second most common subtype of lung cancer, is strongly associated with tobacco smoking and exhibits genomic instability. The cellular origins and molecular processes that contribute to SqCC formation are largely unexplored. Here we show that human basal stem cells (BSCs) isolated from heavy smokers prolifera...

Alternative Titles

Full title

Lung Basal Stem Cells Rapidly Repair DNA Damage Using the Error-Prone Nonhomologous End-Joining Pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1869001603

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1869001603

Other Identifiers

ISSN

1545-7885,1544-9173

E-ISSN

1545-7885

DOI

10.1371/journal.pbio.2000731

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