Oxidative stress-mediated NFκB phosphorylation upregulates p62/SQSTM1 and promotes retinal pigmented...
Oxidative stress-mediated NFκB phosphorylation upregulates p62/SQSTM1 and promotes retinal pigmented epithelial cell survival through increased autophagy
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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p62 is a scaffolding adaptor implicated in the clearance of protein aggregates by autophagy. Reactive oxygen species (ROS) can either stimulate or inhibit NFκB-mediated gene expression influencing cellular fate. We studied the effect of hydrogen peroxide (H2O2)-mediated oxidative stress and NFκB signaling on p62 expression in the retinal pigment ep...
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Oxidative stress-mediated NFκB phosphorylation upregulates p62/SQSTM1 and promotes retinal pigmented epithelial cell survival through increased autophagy
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TN_cdi_plos_journals_1870633097
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1870633097
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0171940
