Suppression of TGF-β pathway by pirfenidone decreases extracellular matrix deposition in ocular fibr...
Suppression of TGF-β pathway by pirfenidone decreases extracellular matrix deposition in ocular fibroblasts in vitro
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
In glaucoma surgery, fibrotic processes occur, leading to impairment of liquid outflow. Activated fibroblasts are responsible for postoperative scarring. The transforming growth factor-β (TGF-β) pathway plays a key role in fibroblast function, differentiation and proliferation. The aim of this study was the characterization of the fibrotic potentia...
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Full title
Suppression of TGF-β pathway by pirfenidone decreases extracellular matrix deposition in ocular fibroblasts in vitro
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TN_cdi_plos_journals_1871525941
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1871525941
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0172592
