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A new synthetic matrix metalloproteinase inhibitor reduces human mesenchymal stem cell adipogenesis

A new synthetic matrix metalloproteinase inhibitor reduces human mesenchymal stem cell adipogenesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1871801004

A new synthetic matrix metalloproteinase inhibitor reduces human mesenchymal stem cell adipogenesis

About this item

Full title

A new synthetic matrix metalloproteinase inhibitor reduces human mesenchymal stem cell adipogenesis

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-02, Vol.12 (2), p.e0172925-e0172925

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Development of adipose tissue requires the differentiation of less specialized cells, such as human mesenchymal stem cells (hMSCs), into adipocytes. Since matrix metalloproteinases (MMPs) play critical roles in the cell differentiation process, we conducted investigations to determine if a novel mercaptosulfonamide-based MMP inhibitor (MMPI), YHJ-7...

Alternative Titles

Full title

A new synthetic matrix metalloproteinase inhibitor reduces human mesenchymal stem cell adipogenesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1871801004

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1871801004

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0172925

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