Log in to save to my catalogue

Toll-like receptor 9 suppresses lupus disease in Fas-sufficient MRL Mice

Toll-like receptor 9 suppresses lupus disease in Fas-sufficient MRL Mice

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1875828201

Toll-like receptor 9 suppresses lupus disease in Fas-sufficient MRL Mice

About this item

Full title

Toll-like receptor 9 suppresses lupus disease in Fas-sufficient MRL Mice

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-03, Vol.12 (3), p.e0173471-e0173471

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Genetic deficiency in TLR9 accelerates pathogenesis in the spontaneous polygenic MRL.Faslpr murine model of systemic lupus erythematosus, despite the absence of anti-nucleosome autoantibodies. However, it could be argued that this result was dependent on Fas-deficiency rather than lupus-promoting genes in the MRL genetic background. Here we report...

Alternative Titles

Full title

Toll-like receptor 9 suppresses lupus disease in Fas-sufficient MRL Mice

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1875828201

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1875828201

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0173471

How to access this item