Toll-like receptor 9 suppresses lupus disease in Fas-sufficient MRL Mice
Toll-like receptor 9 suppresses lupus disease in Fas-sufficient MRL Mice
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Genetic deficiency in TLR9 accelerates pathogenesis in the spontaneous polygenic MRL.Faslpr murine model of systemic lupus erythematosus, despite the absence of anti-nucleosome autoantibodies. However, it could be argued that this result was dependent on Fas-deficiency rather than lupus-promoting genes in the MRL genetic background. Here we report...
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Full title
Toll-like receptor 9 suppresses lupus disease in Fas-sufficient MRL Mice
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TN_cdi_plos_journals_1875828201
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1875828201
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0173471
