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Microstructural white matter alterations in preclinical Alzheimer's disease detected using free wate...

Microstructural white matter alterations in preclinical Alzheimer's disease detected using free wate...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1877382872

Microstructural white matter alterations in preclinical Alzheimer's disease detected using free water elimination diffusion tensor imaging

About this item

Full title

Microstructural white matter alterations in preclinical Alzheimer's disease detected using free water elimination diffusion tensor imaging

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-03, Vol.12 (3), p.e0173982-e0173982

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Brain changes associated with Alzheimer's disease (AD) begin decades before disease diagnosis. While β-amyloid plaques and neurofibrillary tangles are defining features of AD, neuronal loss and synaptic pathology are closely related to the cognitive dysfunction. Brain imaging methods that are tuned to assess degeneration of myelinated nerve fibers...

Alternative Titles

Full title

Microstructural white matter alterations in preclinical Alzheimer's disease detected using free water elimination diffusion tensor imaging

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1877382872

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1877382872

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0173982

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