Inhibition of androgen receptor by decoy molecules delays progression to castration-recurrent prosta...
Inhibition of androgen receptor by decoy molecules delays progression to castration-recurrent prostate cancer
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Androgen receptor (AR) is a member of the steroid receptor family and a therapeutic target for all stages of prostate cancer. AR is activated by ligand binding within its C-terminus ligand-binding domain (LBD). Here we show that overexpression of the AR NTD to generate decoy molecules inhibited both the growth and progression of prostate cancer in...
Alternative Titles
Full title
Inhibition of androgen receptor by decoy molecules delays progression to castration-recurrent prostate cancer
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TN_cdi_plos_journals_1878396767
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1878396767
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0174134
