Palmitic acid is a toll-like receptor 4 ligand that induces human dendritic cell secretion of IL-1β
Palmitic acid is a toll-like receptor 4 ligand that induces human dendritic cell secretion of IL-1β
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Palmitic acid (PA) and other saturated fatty acids are known to stimulate pro-inflammatory responses in human immune cells via Toll-like receptor 4 (TLR4). However, the molecular mechanism responsible for fatty acid stimulation of TLR4 remains unknown. Here, we demonstrate that PA functions as a ligand for TLR4 on human monocyte derived dendritic c...
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Palmitic acid is a toll-like receptor 4 ligand that induces human dendritic cell secretion of IL-1β
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TN_cdi_plos_journals_1894814375
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1894814375
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0176793
