KDM1A/LSD1 regulates the differentiation and maintenance of spermatogonia in mice
KDM1A/LSD1 regulates the differentiation and maintenance of spermatogonia in mice
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The proper regulation of spermatogenesis is crucial to ensure the continued production of sperm and fertility. Here, we investigated the function of the H3K4me2 demethylase KDM1A/LSD1 during spermatogenesis in developing and adult mice. Conditional deletion of Kdm1a in the testis just prior to birth leads to fewer spermatogonia and germ cell loss b...
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Full title
KDM1A/LSD1 regulates the differentiation and maintenance of spermatogonia in mice
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TN_cdi_plos_journals_1898439231
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1898439231
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0177473
