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Comparison of single-marker and multi-marker tests in rare variant association studies of quantitati...

Comparison of single-marker and multi-marker tests in rare variant association studies of quantitati...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1904765452

Comparison of single-marker and multi-marker tests in rare variant association studies of quantitative traits

About this item

Full title

Comparison of single-marker and multi-marker tests in rare variant association studies of quantitative traits

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-05, Vol.12 (5), p.e0178504-e0178504

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

In genetic association studies of rare variants, low statistical power and potential violations of established estimator properties are among the main challenges of association tests. Multi-marker tests (MMTs) have been proposed to target these challenges, but any comparison with single-marker tests (SMTs) has to consider that their aim is to ident...

Alternative Titles

Full title

Comparison of single-marker and multi-marker tests in rare variant association studies of quantitative traits

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1904765452

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1904765452

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0178504

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