Estradiol upregulates voltage-gated sodium channel 1.7 in trigeminal ganglion contributing to hypera...
Estradiol upregulates voltage-gated sodium channel 1.7 in trigeminal ganglion contributing to hyperalgesia of inflamed TMJ
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Full title
Author / Creator
Bi, Rui-Yun , Meng, Zhen , Zhang, Peng , Wang, Xue-Dong , Ding, Yun and Gan, Ye-Hua
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Temporomandibular disorders (TMDs) have the highest prevalence in women of reproductive age. The role of estrogen in TMDs and especially in TMDs related pain is not fully elucidated. Voltage-gated sodium channel 1.7 (Nav1.7) plays a prominent role in pain perception and Nav1.7 in trigeminal ganglion (TG) is involved in the hyperalgesia of inflamed...
Alternative Titles
Full title
Estradiol upregulates voltage-gated sodium channel 1.7 in trigeminal ganglion contributing to hyperalgesia of inflamed TMJ
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Record Identifier
TN_cdi_plos_journals_1906245207
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1906245207
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0178589