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Oxidative stress affects processing of amyloid precursor protein in vascular endothelial cells

Oxidative stress affects processing of amyloid precursor protein in vascular endothelial cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1910318125

Oxidative stress affects processing of amyloid precursor protein in vascular endothelial cells

About this item

Full title

Oxidative stress affects processing of amyloid precursor protein in vascular endothelial cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-06, Vol.12 (6), p.e0178127-e0178127

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Oxidative stress is thought to be a key player in the pathogenesis of neurodegenerative dementia, including Alzheimer's disease (AD). It has been assumed that oxidative stress contributes to the ß-amyloid deposition in cerebral blood vessels.
In order to prove this hypothesis, we examined the effect of oxidative stress on the processing of amylo...

Alternative Titles

Full title

Oxidative stress affects processing of amyloid precursor protein in vascular endothelial cells

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1910318125

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1910318125

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0178127

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