HIV-1 competition experiments in humanized mice show that APOBEC3H imposes selective pressure and pr...
HIV-1 competition experiments in humanized mice show that APOBEC3H imposes selective pressure and promotes virus adaptation
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United States: Public Library of Science
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English
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United States: Public Library of Science
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APOBEC3 (A3) family proteins are DNA cytosine deaminases recognized for contributing to HIV-1 restriction and mutation. Prior studies have demonstrated that A3D, A3F, and A3G enzymes elicit a robust anti-HIV-1 effect in cell cultures and in humanized mouse models. Human A3H is polymorphic and can be categorized into three phenotypes: stable, interm...
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HIV-1 competition experiments in humanized mice show that APOBEC3H imposes selective pressure and promotes virus adaptation
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TN_cdi_plos_journals_1910461767
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1910461767
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1006348
