Sterol 14[alpha]-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana
Sterol 14[alpha]-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana
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Publisher
San Francisco: Public Library of Science
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Language
English
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Publisher
San Francisco: Public Library of Science
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Contents
Amphotericin B has emerged as the therapy of choice for use against the leishmaniases. Administration of the drug in its liposomal formulation as a single injection is being promoted in a campaign to bring the leishmaniases under control. Understanding the risks and mechanisms of resistance is therefore of great importance. Here we select amphoteri...
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Full title
Sterol 14[alpha]-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana
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TN_cdi_plos_journals_1919507250
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1919507250
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ISSN
1935-2727
E-ISSN
1935-2735
DOI
10.1371/journal.pntd.0005649