Log in to save to my catalogue

Sterol 14[alpha]-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana

Sterol 14[alpha]-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1919507250

Sterol 14[alpha]-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana

About this item

Full title

Sterol 14[alpha]-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana

Publisher

San Francisco: Public Library of Science

Journal title

PLoS neglected tropical diseases, 2017-06, Vol.11 (6)

Language

English

Formats

Publication information

Publisher

San Francisco: Public Library of Science

More information

Scope and Contents

Contents

Amphotericin B has emerged as the therapy of choice for use against the leishmaniases. Administration of the drug in its liposomal formulation as a single injection is being promoted in a campaign to bring the leishmaniases under control. Understanding the risks and mechanisms of resistance is therefore of great importance. Here we select amphoteri...

Alternative Titles

Full title

Sterol 14[alpha]-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1919507250

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1919507250

Other Identifiers

ISSN

1935-2727

E-ISSN

1935-2735

DOI

10.1371/journal.pntd.0005649

How to access this item