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Patients experiencing statin-induced myalgia exhibit a unique program of skeletal muscle gene expres...

Patients experiencing statin-induced myalgia exhibit a unique program of skeletal muscle gene expres...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1925834840

Patients experiencing statin-induced myalgia exhibit a unique program of skeletal muscle gene expression following statin re-challenge

About this item

Full title

Patients experiencing statin-induced myalgia exhibit a unique program of skeletal muscle gene expression following statin re-challenge

Publisher

United States: Public Library of Science

Journal title

PloS one, 2017-08, Vol.12 (8), p.e0181308-e0181308

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Statins, the 3-hydroxy-3-methyl-glutaryl (HMG)-CoA reductase inhibitors, are widely prescribed for treatment of hypercholesterolemia. Although statins are generally well tolerated, up to ten percent of statin-treated patients experience myalgia symptoms, defined as muscle pain without elevated creatinine phosphokinase (CPK) levels. Myalgia is the m...

Alternative Titles

Full title

Patients experiencing statin-induced myalgia exhibit a unique program of skeletal muscle gene expression following statin re-challenge

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1925834840

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1925834840

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0181308

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