Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particle...
Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Parkinson's disease (PD) is a progressive and currently incurable neurological disorder characterised by the loss of midbrain dopaminergic neurons and the accumulation of aggregated alpha-synuclein (a-syn). Oligomeric a-syn is proposed to play a central role in spreading protein aggregation in the brain with associated cellular toxicity contributin...
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Full title
Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles
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TN_cdi_plos_journals_1927791343
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1927791343
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0181844
