The selective PI3Kα inhibitor BYL719 as a novel therapeutic option for neuroendocrine tumors: Result...
The selective PI3Kα inhibitor BYL719 as a novel therapeutic option for neuroendocrine tumors: Results from multiple cell line models
About this item
Full title
Author / Creator
Nölting, Svenja , Rentsch, Jakob , Freitag, Helma , Detjen, Katharina , Briest, Franziska , Möbs, Markus , Weissmann, Victoria , Siegmund, Britta , Auernhammer, Christoph J , Aristizabal Prada, Elke Tatjana , Lauseker, Michael , Grossman, Ashley , Exner, Samantha , Fischer, Christian , Grötzinger, Carsten , Schrader, Jörg , Grabowski, Patricia , GERMAN NET-Z study group and on behalf of the GERMAN NET-Z study group
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
The therapeutic options for metastatic neuroendocrine tumors (NETs) are limited. As PI3K signaling is often activated in NETs, we have assessed the effects of selective PI3Kp110α inhibition by the novel agent BYL719 on cell viability, colony formation, apoptosis, cell cycle, signaling pathways, differentiation and secretion in pancreatic (BON-1, QG...
Alternative Titles
Full title
The selective PI3Kα inhibitor BYL719 as a novel therapeutic option for neuroendocrine tumors: Results from multiple cell line models
Authors, Artists and Contributors
Author / Creator
Rentsch, Jakob
Freitag, Helma
Detjen, Katharina
Briest, Franziska
Möbs, Markus
Weissmann, Victoria
Siegmund, Britta
Auernhammer, Christoph J
Aristizabal Prada, Elke Tatjana
Lauseker, Michael
Grossman, Ashley
Exner, Samantha
Fischer, Christian
Grötzinger, Carsten
Schrader, Jörg
Grabowski, Patricia
GERMAN NET-Z study group
on behalf of the GERMAN NET-Z study group
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1927973172
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1927973172
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0182852
