Highly efficient gene inactivation by adenoviral CRISPR/Cas9 in human primary cells
Highly efficient gene inactivation by adenoviral CRISPR/Cas9 in human primary cells
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Phenotypic assays using human primary cells are highly valuable tools for target discovery and validation in drug discovery. Expression knockdown (KD) of such targets in these assays allows the investigation of their role in models of disease processes. Therefore, efficient and fast modes of protein KD in phenotypic assays are required. The CRISPR/...
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Full title
Highly efficient gene inactivation by adenoviral CRISPR/Cas9 in human primary cells
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TN_cdi_plos_journals_1927973392
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1927973392
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0182974
