Tankyrase inhibitors suppress hepatocellular carcinoma cell growth via modulating the Hippo cascade
Tankyrase inhibitors suppress hepatocellular carcinoma cell growth via modulating the Hippo cascade
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Previous data indicate that Tankyrase inhibitors exert anti-growth functions in many cancer cell lines due to their ability to inactivate the YAP protooncogene. In the present manuscript, we investigated the effect of Tankyrase inhibitors on the growth of hepatocellular carcinoma (HCC) cell lines and the molecular mechanisms involved. For this purp...
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Tankyrase inhibitors suppress hepatocellular carcinoma cell growth via modulating the Hippo cascade
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TN_cdi_plos_journals_1936206894
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1936206894
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0184068