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Domain-based prediction of the human isoform interactome provides insights into the functional impac...

Domain-based prediction of the human isoform interactome provides insights into the functional impac...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1939435678

Domain-based prediction of the human isoform interactome provides insights into the functional impact of alternative splicing

About this item

Full title

Domain-based prediction of the human isoform interactome provides insights into the functional impact of alternative splicing

Publisher

United States: Public Library of Science

Journal title

PLoS computational biology, 2017-08, Vol.13 (8), p.e1005717-e1005717

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Alternative splicing is known to remodel protein-protein interaction networks ("interactomes"), yet large-scale determination of isoform-specific interactions remains challenging. We present a domain-based method to predict the isoform interactome from the reference interactome. First, we construct the domain-resolved reference interactome by mappi...

Alternative Titles

Full title

Domain-based prediction of the human isoform interactome provides insights into the functional impact of alternative splicing

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1939435678

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1939435678

Other Identifiers

ISSN

1553-7358,1553-734X

E-ISSN

1553-7358

DOI

10.1371/journal.pcbi.1005717

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