The histone variant macroH2A confers functional robustness to the intestinal stem cell compartment
The histone variant macroH2A confers functional robustness to the intestinal stem cell compartment
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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A stem cell's epigenome directs cell fate during development, homeostasis, and regeneration. Epigenetic dysregulation can lead to inappropriate cell fate decisions, aberrant cell function, and even cancer. The histone variant macroH2A has been shown to influence gene expression, guide cell fate, and safeguard against genotoxic stress. Interestingly...
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Full title
The histone variant macroH2A confers functional robustness to the intestinal stem cell compartment
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TN_cdi_plos_journals_1943112845
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1943112845
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0185196
