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RhoGEF9 splice isoforms influence neuronal maturation and synapse formation downstream of [alpha] 2...

RhoGEF9 splice isoforms influence neuronal maturation and synapse formation downstream of [alpha] 2...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1965077706

RhoGEF9 splice isoforms influence neuronal maturation and synapse formation downstream of [alpha] 2 GABAA receptors

About this item

Full title

RhoGEF9 splice isoforms influence neuronal maturation and synapse formation downstream of [alpha] 2 GABAA receptors

Publisher

San Francisco: Public Library of Science

Journal title

PLoS genetics, 2017-10, Vol.13 (10)

Language

English

Formats

Publication information

Publisher

San Francisco: Public Library of Science

More information

Scope and Contents

Contents

In developing brain neuronal migration, dendrite outgrowth and dendritic spine outgrowth are controlled by Cdc42, a small GTPase of the Rho family, and its activators. Cdc42 function in promoting actin polymerization is crucial for glutamatergic synapse regulation. Here, we focus on GABAergic synapse-specific activator of Cdc42, collybistin (CB) an...

Alternative Titles

Full title

RhoGEF9 splice isoforms influence neuronal maturation and synapse formation downstream of [alpha] 2 GABAA receptors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1965077706

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1965077706

Other Identifiers

ISSN

1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1007073

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