Enrichment of colorectal cancer associations in functional regions: Insight for using epigenomics da...
Enrichment of colorectal cancer associations in functional regions: Insight for using epigenomics data in the analysis of whole genome sequence-imputed GWAS data
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Author / Creator
GECCO and CCFR , on behalf of GECCO and CCFR , Bien, Stephanie A , Auer, Paul L , Harrison, Tabitha A , Qu, Conghui , Connolly, Charles M , Greenside, Peyton G , Chen, Sai , Berndt, Sonja I , Bézieau, Stéphane , Kang, Hyun M , Huyghe, Jeroen , Brenner, Hermann , Casey, Graham , Chan, Andrew T , Hopper, John L , Banbury, Barbara L , Chang-Claude, Jenny , Chanock, Stephen J , Haile, Robert W , Hoffmeister, Michael , Fuchsberger, Christian , Jenkins, Mark A , Leal, Suzanne M , Lemire, Mathieu , Newcomb, Polly A , Gallinger, Steven , Potter, John D , Schoen, Robert E , Slattery, Martha L , Smith, Joshua D , Le Marchand, Loic , White, Emily , Zanke, Brent W , Abeçasis, Goncalo R , Carlson, Christopher S , Peters, Ulrike , Nickerson, Deborah A , Kundaje, Anshul and Hsu, Li
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
The evaluation of less frequent genetic variants and their effect on complex disease pose new challenges for genomic research. To investigate whether epigenetic data can be used to inform aggregate rare-variant association methods (RVAM), we assessed whether variants more significantly associated with colorectal cancer (CRC) were preferentially loc...
Alternative Titles
Full title
Enrichment of colorectal cancer associations in functional regions: Insight for using epigenomics data in the analysis of whole genome sequence-imputed GWAS data
Authors, Artists and Contributors
Author / Creator
on behalf of GECCO and CCFR
Bien, Stephanie A
Auer, Paul L
Harrison, Tabitha A
Qu, Conghui
Connolly, Charles M
Greenside, Peyton G
Chen, Sai
Berndt, Sonja I
Bézieau, Stéphane
Kang, Hyun M
Huyghe, Jeroen
Brenner, Hermann
Casey, Graham
Chan, Andrew T
Hopper, John L
Banbury, Barbara L
Chang-Claude, Jenny
Chanock, Stephen J
Haile, Robert W
Hoffmeister, Michael
Fuchsberger, Christian
Jenkins, Mark A
Leal, Suzanne M
Lemire, Mathieu
Newcomb, Polly A
Gallinger, Steven
Potter, John D
Schoen, Robert E
Slattery, Martha L
Smith, Joshua D
Le Marchand, Loic
White, Emily
Zanke, Brent W
Abeçasis, Goncalo R
Carlson, Christopher S
Peters, Ulrike
Nickerson, Deborah A
Kundaje, Anshul
Hsu, Li
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1967046950
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1967046950
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0186518
