Variant B cell receptor isotype functions differ in hairy cell leukemia with mutated BRAF and IGHV g...
Variant B cell receptor isotype functions differ in hairy cell leukemia with mutated BRAF and IGHV genes
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Publisher
United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
A functional B-cell receptor (BCR) is critical for survival of normal B-cells, but whether it plays a comparable role in B-cell malignancy is as yet not fully delineated. Typical Hairy Cell Leukemia (HCL) is a rare B-cell tumor, and unique in expressing multiple surface immunoglobulin (sIg) isotypes on individual tumor cells (mult-HCL), to raise qu...
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Full title
Variant B cell receptor isotype functions differ in hairy cell leukemia with mutated BRAF and IGHV genes
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TN_cdi_plos_journals_1977446055
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1977446055
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0086556
