Characterization of niphatenones that inhibit androgen receptor N-terminal domain
Characterization of niphatenones that inhibit androgen receptor N-terminal domain
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Androgen ablation therapy causes a temporary reduction in tumor burden in patients with advanced prostate cancer. Unfortunately the malignancy will return to form lethal castration-recurrent prostate cancer (CRPC). The androgen receptor (AR) remains transcriptionally active in CRPC in spite of castrate levels of androgens in the blood. AR transcrip...
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Full title
Characterization of niphatenones that inhibit androgen receptor N-terminal domain
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TN_cdi_plos_journals_1979816572
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1979816572
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0107991