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Galectin-3 up-regulation in hypoxic and nutrient deprived microenvironments promotes cell survival

Galectin-3 up-regulation in hypoxic and nutrient deprived microenvironments promotes cell survival

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1979937368

Galectin-3 up-regulation in hypoxic and nutrient deprived microenvironments promotes cell survival

About this item

Full title

Galectin-3 up-regulation in hypoxic and nutrient deprived microenvironments promotes cell survival

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-11, Vol.9 (11), p.e111592-e111592

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Galectin-3 (gal-3) is a β-galactoside binding protein related to many tumoral aspects, e.g. angiogenesis, cell growth and motility and resistance to cell death. Evidence has shown its upregulation upon hypoxia, a common feature in solid tumors such as glioblastoma multiformes (GBM). This tumor presents a unique feature described as pseudopalisading...

Alternative Titles

Full title

Galectin-3 up-regulation in hypoxic and nutrient deprived microenvironments promotes cell survival

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1979937368

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1979937368

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0111592

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