Evaluation of RNAi and CRISPR technologies by large-scale gene expression profiling in the Connectiv...
Evaluation of RNAi and CRISPR technologies by large-scale gene expression profiling in the Connectivity Map
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The application of RNA interference (RNAi) to mammalian cells has provided the means to perform phenotypic screens to determine the functions of genes. Although RNAi has revolutionized loss-of-function genetic experiments, it has been difficult to systematically assess the prevalence and consequences of off-target effects. The Connectivity Map (CMA...
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Evaluation of RNAi and CRISPR technologies by large-scale gene expression profiling in the Connectivity Map
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TN_cdi_plos_journals_1989018149
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1989018149
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ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.2003213
