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ArticlesPeer ReviewedFull Text
Decoupling epithelial-mesenchymal transitions from stromal profiles by integrative expression analysis
Author / Creator:Tyler, Michael ; Tirosh, Itay
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-05, Vol.12 (1), p.2592-2592, Article 2592
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Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action
Author / Creator:McFarland, James M. ; Paolella, Brenton R. ; Warren, Allison ; Geiger-Schuller, Kathryn ; Shibue, Tsukasa ; Rothberg, Michael ; Kuksenko, Olena ; Colgan, William N. ; Jones, Andrew ; Chambers, Emily ; Dionne, Danielle ; Bender, Samantha ; Wolpin, Brian M. ; Ghandi, Mahmoud ; Tirosh, Itay ; Rozenblatt-Rosen, Orit ; Roth, Jennifer A. ; Golub, Todd R. ; Regev, Aviv ; Aguirre, Andrew J. ; Vazquez, Francisca ; Tsherniak, Aviad
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-08, Vol.11 (1), p.4296-15, Article 4296
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Challenges and emerging directions in single-cell analysis
Author / Creator:Yuan, Guo-Cheng ; Cai, Long ; Elowitz, Michael ; Enver, Tariq ; Fan, Guoping ; Guo, Guoji ; Irizarry, Rafael ; Kharchenko, Peter ; Kim, Junhyong ; Orkin, Stuart ; Quackenbush, John ; Saadatpour, Assieh ; Schroeder, Timm ; Shivdasani, Ramesh ; Tirosh, Itay
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology, 2017-05, Vol.18 (1), p.84-84, Article 84
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ArticlesPeer ReviewedFull Text
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
Author / Creator:Patel, Anoop P. ; Tirosh, Itay ; Trombetta, John J. ; Shalek, Alex K. ; Gillespie, Shawn M. ; Wakimoto, Hiroaki ; Cahill, Daniel P. ; Nahed, Brian V. ; Curry, William T. ; Martuza, Robert L. ; Louis, David N. ; Rozenblatt-Rosen, Orit ; Suvà, Mario L. ; Regev, Aviv ; Bernstein, Bradley E.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2014-06, Vol.344 (6190), p.1396-1401
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ArticlesPeer ReviewedFull Text
A single-cell landscape of high-grade serous ovarian cancer
Author / Creator:Izar, Benjamin ; Tirosh, Itay ; Stover, Elizabeth H. ; Wakiro, Isaac ; Cuoco, Michael S. ; Alter, Idan ; Rodman, Christopher ; Leeson, Rachel ; Su, Mei-Ju ; Shah, Parin ; Iwanicki, Marcin ; Walker, Sarah R. ; Kanodia, Abhay ; Melms, Johannes C. ; Mei, Shaolin ; Lin, Jia-Ren ; Porter, Caroline B. M. ; Slyper, Michal ; Waldman, Julia ; Jerby-Arnon, Livnat ; Ashenberg, Orr ; Brinker, Titus J. ; Mills, Caitlin ; Rogava, Meri ; Vigneau, Sébastien ; Sorger, Peter K. ; Garraway, Levi A. ; Konstantinopoulos, Panagiotis A. ; Liu, Joyce F. ; Matulonis, Ursula ; Johnson, Bruce E. ; Rozenblatt-Rosen, Orit ; Rotem, Asaf ; Regev, Aviv
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2020-08, Vol.26 (8), p.1271-1279
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Evaluation of RNAi and CRISPR technologies by large-scale gene expression profiling in the Connectivity Map
Author / Creator:Smith, Ian ; Greenside, Peyton G. ; Natoli, Ted ; Lahr, David L. ; Wadden, David ; Tirosh, Itay ; Narayan, Rajiv ; Root, David E. ; Golub, Todd R. ; Subramanian, Aravind ; Doench, John G.
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2017-11, Vol.15 (11), p.e2003213-e2003213
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Genome-wide CRISPR screen identifies PRC2 and KMT2D-COMPASS as regulators of distinct EMT trajectories that contribute differentially to metastasis
Author / Creator:Zhang, Yun ; Donaher, Joana Liu ; Das, Sunny ; Li, Xin ; Reinhardt, Ferenc ; Krall, Jordan A. ; Lambert, Arthur W. ; Thiru, Prathapan ; Keys, Heather R. ; Khan, Mehreen ; Hofree, Matan ; Wilson, Molly M. ; Yedier-Bayram, Ozlem ; Lack, Nathan A. ; Onder, Tamer T. ; Bagci-Onder, Tugba ; Tyler, Michael ; Tirosh, Itay ; Regev, Aviv ; Lees, Jacqueline A. ; Weinberg, Robert A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2022-04, Vol.24 (4), p.554-564
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ArticlesPeer ReviewedFull Text
A genetic signature of interspecies variations in gene expression
Author / Creator:Tirosh, Itay ; Weinberger, Adina ; Carmi, Miri ; Barkai, Naama
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2006-07, Vol.38 (7), p.830-834
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ArticlesPeer ReviewedFull Text
Coupled Evolution of Transcription and mRNA Degradation
Author / Creator:Dori-Bachash, Mally ; Shema, Efrat ; Tirosh, Itay
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2011-07, Vol.9 (7), p.e1001106-e1001106
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ArticlesPeer ReviewedFull Text
Elucidating the diversity of malignant mesenchymal states in glioblastoma by integrative analysis
Author / Creator:Chanoch-Myers, Rony ; Wider, Adi ; Suva, Mario L. ; Tirosh, Itay
Publisher:London: BioMed Central Ltd
Journal title:Genome medicine, 2022-09, Vol.14 (1), p.1-106, Article 106
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ArticlesPeer ReviewedFull Text
Correction: Elucidating the diversity of malignant mesenchymal states in glioblastoma by integrative analysis
Author / Creator:Chanoch-Myers, Rony ; Wider, Adi ; Suva, Mario L. ; Tirosh, Itay
Publisher:London: BioMed Central Ltd
Journal title:Genome medicine, 2022-10, Vol.14 (1), p.1-117, Article 117
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Nasopharyngeal carcinoma joins the single‐cell party
Author / Creator:Mints, Michael ; Tirosh, Itay
Publisher:United States: John Wiley & Sons, Inc
Journal title:Cancer communications (London, England), 2020-09, Vol.40 (9), p.453-455
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ArticlesPeer ReviewedFull Text
Divergence of nucleosome positioning between two closely related yeast species: genetic basis and functional consequences
Author / Creator:Tirosh, Itay ; Sigal, Nadejda ; Barkai, Naama
Publisher:London: Nature Publishing Group UK
Journal title:Molecular systems biology, 2010-05, Vol.6 (1), p.365-n/a
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miR-142 orchestrates a network of actin cytoskeleton regulators during megakaryopoiesis
Author / Creator:Chapnik, Elik ; Rivkin, Natalia ; Mildner, Alexander ; Beck, Gilad ; Pasvolsky, Ronit ; Metzl-Raz, Eyal ; Birger, Yehudit ; Amir, Gail ; Tirosh, Itay ; Porat, Ziv ; Israel, Liron L ; Lellouche, Emmanuel ; Michaeli, Shulamit ; Lellouche, Jean-Paul M ; Izraeli, Shai ; Jung, Steffen ; Hornstein, Eran
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2014-05, Vol.3, p.e01964-e01964
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ArticlesPeer ReviewedFull Text
Inferring regulatory mechanisms from patterns of evolutionary divergence
Author / Creator:Tirosh, Itay ; Barkai, Naama
Publisher:London: Nature Publishing Group UK
Journal title:Molecular systems biology, 2011-09, Vol.7 (1), p.530-n/a
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Malignant cell-specific CXCL14 promotes tumor lymphocyte infiltration in oral cavity squamous cell carcinoma
Author / Creator:Parikh, Anuraag ; Shin, JuneHo ; Faquin, William ; Lin, Derrick T ; Tirosh, Itay ; Sunwoo, John B ; Puram, Sidharth V
Publisher:England: BMJ Publishing Group Ltd
Journal title:Journal for immunotherapy of cancer, 2020-09, Vol.8 (2), p.e001048
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Chromatin regulators as capacitors of interspecies variations in gene expression
Author / Creator:Tirosh, Itay ; Reikhav, Sharon ; Sigal, Nadejda ; Assia, Yael ; Barkai, Naama
Publisher:London: Nature Publishing Group UK
Journal title:Molecular systems biology, 2010-11, Vol.6 (1), p.435-n/a
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Extensive divergence of yeast stress responses through transitions between induced and constitutive activation
Author / Creator:Tirosh, Itay ; Wong, Koon Ho ; Barkai, Naama ; Struhl, Kevin
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (40), p.16693-16698
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ArticlesPeer ReviewedFull Text
Widespread promoter-mediated coordination of transcription and mRNA degradation
Author / Creator:Dori-Bachash, Mally ; Shalem, Ophir ; Manor, Yair S ; Pilpel, Yitzhak ; Tirosh, Itay
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology (Online Edition), 2012-12, Vol.13 (12), p.R114-R114, Article R114
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Epigenetically-Inherited Centromere and Neocentromere DNA Replicates Earliest in S-Phase
Author / Creator:Koren, Amnon ; Tsai, Hung-Ji ; Tirosh, Itay ; Burrack, Laura S. ; Barkai, Naama ; Berman, Judith
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2010-08, Vol.6 (8), p.e1001068-e1001068
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Showing 1 to 20 of 56 results

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Decoupling epithelial-mesenchymal transitions from stromal profiles by integrative expression analysis

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Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action

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Challenges and emerging directions in single-cell analysis

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Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

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A single-cell landscape of high-grade serous ovarian cancer

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Evaluation of RNAi and CRISPR technologies by large-scale gene expression profiling in the Connectivity Map

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Genome-wide CRISPR screen identifies PRC2 and KMT2D-COMPASS as regulators of distinct EMT trajectories that contribute differentially to metastasis

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A genetic signature of interspecies variations in gene expression

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Coupled Evolution of Transcription and mRNA Degradation

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Elucidating the diversity of malignant mesenchymal states in glioblastoma by integrative analysis

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Correction: Elucidating the diversity of malignant mesenchymal states in glioblastoma by integrative analysis

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Nasopharyngeal carcinoma joins the single‐cell party

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Divergence of nucleosome positioning between two closely related yeast species: genetic basis and functional consequences

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miR-142 orchestrates a network of actin cytoskeleton regulators during megakaryopoiesis

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Inferring regulatory mechanisms from patterns of evolutionary divergence

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Malignant cell-specific CXCL14 promotes tumor lymphocyte infiltration in oral cavity squamous cell carcinoma

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Chromatin regulators as capacitors of interspecies variations in gene expression

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Extensive divergence of yeast stress responses through transitions between induced and constitutive activation

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Widespread promoter-mediated coordination of transcription and mRNA degradation

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Epigenetically-Inherited Centromere and Neocentromere DNA Replicates Earliest in S-Phase

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