Identification of an elaborate NK-specific system regulating HLA-C expression
Identification of an elaborate NK-specific system regulating HLA-C expression
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
The HLA-C gene appears to have evolved in higher primates to serve as a dominant source of ligands for the KIR2D family of inhibitory MHC class I receptors. The expression of NK cell-intrinsic MHC class I has been shown to regulate the murine Ly49 family of MHC class I receptors due to the interaction of these receptors with NK cell MHC in cis. How...
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Full title
Identification of an elaborate NK-specific system regulating HLA-C expression
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TN_cdi_plos_journals_2002619052
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2002619052
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1007163
