Kinetic characterization and allosteric inhibition of the Yersinia pestis 1-deoxy-D-xylulose 5-phosp...
Kinetic characterization and allosteric inhibition of the Yersinia pestis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase)
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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The methylerythritol phosphate (MEP) pathway found in many bacteria governs the synthesis of isoprenoids, which are crucial lipid precursors for vital cell components such as ubiquinone. Because mammals synthesize isoprenoids via an alternate pathway, the bacterial MEP pathway is an attractive target for novel antibiotic development, necessitated b...
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Full title
Kinetic characterization and allosteric inhibition of the Yersinia pestis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase)
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TN_cdi_plos_journals_2014389445
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2014389445
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0106243
