TNF-α blockade impairs in vitro tuberculous granuloma formation and down modulate Th1, Th17 and Treg...
TNF-α blockade impairs in vitro tuberculous granuloma formation and down modulate Th1, Th17 and Treg cytokines
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Tuberculosis (TB) is a granulomatous disease that has affected humanity for thousands of years. The production of cytokines, such as IFN-γ and TNF-α, is fundamental in the formation and maintenance of granulomas and in the control of the disease. Recently, the introduction of TNF-α-blocking monoclonal antibodies, such as Infliximab, has brought imp...
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Full title
TNF-α blockade impairs in vitro tuberculous granuloma formation and down modulate Th1, Th17 and Treg cytokines
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TN_cdi_plos_journals_2014398128
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2014398128
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0194430
