Systems-based analyses of brain regions functionally impacted in Parkinson's disease reveals underly...
Systems-based analyses of brain regions functionally impacted in Parkinson's disease reveals underlying causal mechanisms
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Detailed analysis of disease-affected tissue provides insight into molecular mechanisms contributing to pathogenesis. Substantia nigra, striatum, and cortex are functionally connected with increasing degrees of alpha-synuclein pathology in Parkinson's disease. We undertook functional and causal pathway analysis of gene expression and proteomic alte...
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Full title
Systems-based analyses of brain regions functionally impacted in Parkinson's disease reveals underlying causal mechanisms
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TN_cdi_plos_journals_2014420783
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_2014420783
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0102909
